LTB antibody (FITC)

Catalog No. ABIN1710265

This Rabbit Polyclonal antibody specifically detects LTB in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LTB antibody (FITC) (ABIN1710265)

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTB antibody is conjugated to FITC

Application: Western Blotting (WB)

Product Details anti-LTB Antibody (FITC)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Lymphotoxin Beta

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LTB

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Alternative Name: Lymphotoxin beta

Background:

Synonyms: LT beta, LT-beta, LTB, lymphotoxin beta TNF superfamily, member 3, lymphotoxin beta, lymphotoxin-beta, OTTHUMP00000038214, p33, TNF C, TNF-C, TNFC, TNFC_HUMAN, TNFSF3, tumor necrosis factor C lymphotoxin beta, tumor necrosis factor C, tumor necrosis factor ligand superfamily member 3.

Background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID: 4050

UniProt: Q06643

Pathways: NF-kappaB Signaling