THEMIS antibody (AA 301-400) (FITC)

Catalog No. ABIN1710334

This Rabbit Polyclonal antibody specifically detects THEMIS in WB, IF (cc) and IF (p). It exhibits reactivity toward Human and Rat.

Quick Overview for THEMIS antibody (AA 301-400) (FITC) (ABIN1710334)

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEMIS antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-THEMIS Antibody (FITC)

Binding Specificity: AA 301-400

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human THEMIS

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for THEMIS

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Alternative Name: THEMIS

Background:

Synonyms: GASP, SPOT, TSEPA, C6orf190, C6orf207, bA325O24.3, bA325O24.4, Protein THEMIS, Thymocyte-expressed molecule involved in selection, THEMIS

Background: Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity).

Gene ID: 387357

UniProt: Q8N1K5