HES7 antibody (AA 21-100) (FITC)

Catalog No. ABIN1710531

This anti-HES7 antibody is a Rabbit Polyclonal antibody detecting HES7 in IF (cc), IF (p). Suitable for Human.

Quick Overview for HES7 antibody (AA 21-100) (FITC) (ABIN1710531)

Target: HES7 (Hairy and Enhancer of Split 7 (HES7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HES7 antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HES7 Antibody (FITC)

Binding Specificity: AA 21-100

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HES7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HES7

Target: HES7 (Hairy and Enhancer of Split 7 (HES7))

Alternative Name: HES7

Background:

Synonyms: bHLH factor Hes7, bHLHb37, Class B basic helix loop helix protein 37, Class B basic helix-loop-helix protein 37, hairy and enhancer of split 7, Hes7, HES7_HUMAN, hHes7, SCDO4, Transcription factor HES 7, Transcription factor HES-7.

Background: HES7 is a 225 amino acid transcriptional repressor protein. Localized to the nucleus, HES7 represses transcription of N box- and E box-containing promoters. HES7, along with family member HES1, is thought to cooperatively regulate somite formation in the presomitic mesoderm. HES7 may also be essential for coordinated somite segmentation by acting as a segmentation clock. HES7 contains one basic helix-loop-helix (bHLH) domain and one Orange domain. Mutations in HES7 have been found to cause spondylocostal dysostosis, an autosomal recessive disorder characterized by deformities of the chest and spine.

Gene ID: 84667