EFCAB12 antibody (AA 421-520) (HRP)

Catalog No. ABIN1710927

This anti-EFCAB12 antibody is a Rabbit Polyclonal antibody detecting EFCAB12 in ELISA, WB, IHC (fro), IHC (p). Suitable for Human.

Quick Overview for EFCAB12 antibody (AA 421-520) (HRP) (ABIN1710927)

Target: EFCAB12 (EF-Hand Calcium Binding Domain 12 (EFCAB12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFCAB12 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-EFCAB12 Antibody (HRP)

Binding Specificity: AA 421-520

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C3orf25

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EFCAB12

Target: EFCAB12 (EF-Hand Calcium Binding Domain 12 (EFCAB12))

Alternative Name: C3orf25

Background:

Synonyms: C3orf25, EF-hand domain-containing protein C3orf25, EFC12_HUMAN.

Background: Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. The C3orf25 gene product has been provisionally designated C3orf25 pending further characterization.