GPR146 antibody (AA 221-320) (HRP)

Catalog No. ABIN1711013

The Rabbit Polyclonal anti-GPR146 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect GPR146 in samples from Human.

Quick Overview for GPR146 antibody (AA 221-320) (HRP) (ABIN1711013)

Target: GPR146 (G Protein-Coupled Receptor 146 (GPR146))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR146 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPR146 Antibody (HRP)

Binding Specificity: AA 221-320

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 146

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GPR146

Target: GPR146 (G Protein-Coupled Receptor 146 (GPR146))

Alternative Name: GPR146

Background:

Synonyms: G protein coupled receptor 146, G-protein coupled receptor PGR8, GP146_HUMAN, GPR146, PGR8, Probable G-protein coupled receptor 146, GPCR GPR146.

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR146 (G protein-coupled receptor 146), also known as PGR8, is a 333 amino acid multi-pass transmembrane protein that belongs to the G-protein coupled receptor 1 family. Characterized as an orphan receptor for which its endogenous ligand has yet to be identified, GPR146 is thought to play a role in signaling events throughout the cell.

Gene ID: 115330

UniProt: Q96CH1