IdnK antibody (AA 51-150) (HRP)

Catalog No. ABIN1711174

This Rabbit Polyclonal antibody specifically detects IdnK in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for IdnK antibody (AA 51-150) (HRP) (ABIN1711174)

Target: IdnK (IDNK) (IdnK Gluconokinase Homolog (IDNK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IdnK antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IdnK Antibody (HRP)

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf103

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IdnK

Target: IdnK (IDNK) (IdnK Gluconokinase Homolog (IDNK))

Alternative Name: C9orf103

Background:

Synonyms: bA522I20.2, C9orf103, Chromosome 9 open reading frame 103, Glucokinase like protein, Gluconate kinase, Gluconokinase like protein, GNTK_HUMAN, IDNK, OTTHUMP00000021546, OTTHUMP00000021547, Probable gluconokinase, RP11-522I20.2.

Background: C9orf103 (chromosome 9 open reading frame 103), also known as gluconate kinase, is a 187 amino acid protein that belongs to the gluconokinase gntK/gntV family and catalyzes the conversion of ATP and D-gluconate to ADP and 6-D-gluconate. Existing as three alternatively spliced isoforms, the gene encoding C9orf103 maps to human chromosome 9q21.32. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Gene ID: 414328