G Protein-Coupled Receptor 110 antibody (AA 51-150) (HRP)

Catalog No. ABIN1711177

This Rabbit Polyclonal antibody specifically detects G Protein-Coupled Receptor 110 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Mouse.

Quick Overview for G Protein-Coupled Receptor 110 antibody (AA 51-150) (HRP) (ABIN1711177)

Target: G Protein-Coupled Receptor 110 (GPR110)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G Protein-Coupled Receptor 110 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-G Protein-Coupled Receptor 110 Antibody (HRP)

Binding Specificity: AA 51-150

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 110

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for G Protein-Coupled Receptor 110

Target: G Protein-Coupled Receptor 110 (GPR110)

Alternative Name: GPR110

Background:

Synonyms: PGR19, GPR110, KPG_012, hGPCR36, Adhesion G-protein coupled receptor F1, G-protein coupled receptor 110, G-protein coupled receptor KPG_012, G-protein coupled receptor PGR19, ADGRF1

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911 amino acid protein that belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Characterized as an adhesion GPCR, GPR110 is a multipass membrane-bound protein with a long amino-terminus that contains multiple domains. One of these domains is the GPCR proteolytic site (GPS), which is essential for proteolytic cleavage of the amino-terminus and for cell surface expression.

Gene ID: 266977

UniProt: Q5T601