BRD3 antibody (AA 601-700) (HRP)

Catalog No. ABIN1711634

The Rabbit Polyclonal anti-BRD3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect BRD3 in samples from Human.

Quick Overview for BRD3 antibody (AA 601-700) (HRP) (ABIN1711634)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BRD3 Antibody (HRP)

Binding Specificity: AA 601-700

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BRD3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Alternative Name: BRD3

Background:

Synonyms: BRD 3, Brd3, BRD3_HUMAN, Bromodomain containing 3, Bromodomain containing protein 3, Bromodomain-containing protein 3, KIAA0043, Open reading frame X, ORFX, RING3 like gene, RING3-like protein, RING3L.

Background: The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.

Gene ID: 8019

Pathways: Chromatin Binding