EXOSC7 antibody (AA 21-120) (HRP)

Catalog No. ABIN1711669

This Rabbit Polyclonal antibody specifically detects EXOSC7 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Rat.

Quick Overview for EXOSC7 antibody (AA 21-120) (HRP) (ABIN1711669)

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC7 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-EXOSC7 Antibody (HRP)

Binding Specificity: AA 21-120

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXOSC7

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EXOSC7

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Alternative Name: EXOSC7

Background:

Synonyms: EAP1, EXOS7_HUMAN, Exosc7, Exosome complex component RRP42, Exosome complex exonuclease RRP42, Exosome component 7, FLJ26543, hRrp42p, KIAA0116, p8, Ribosomal RNA processing protein 42, Ribosomal RNA-processing protein 42, RRP42, Rrp42p.

Background: The exosome is a multisubunit complex of 3? to 5? exoribonucleases. It is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements in their untranslated 3? region. EXOSC7 (exosome component 7), also known as p8, EAP1, RRP42 (Ribosomal RNA-processing protein 42), Rrp42p or hRrp42p, is a component of the exosome multienzyme ribonuclease complex. It belongs to the RNase PH family and localizes to the nucleolus. EXOSC7 is one of the six RNase-PH domain subunits of the exosome. Together, these six subunits form a PNPase-like ring. EXOSC7 is required for the processing of the 7S pre-RNA.

Gene ID: 23016