MOBKL3 antibody (AA 101-200) (HRP)

Catalog No. ABIN1711834

This Rabbit Polyclonal antibody specifically detects MOBKL3 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for MOBKL3 antibody (AA 101-200) (HRP) (ABIN1711834)

Target: MOBKL3 (MOB Family Member 4, Phocein (MOBKL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOBKL3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MOBKL3 Antibody (HRP)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PREI3/Phocein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MOBKL3

Target: MOBKL3 (MOB Family Member 4, Phocein (MOBKL3))

Alternative Name: PREI3/Phocein

Background:

Synonyms: 2C4D, CGI 95, class II mMOB1, MGC12264, MOB family member 4, phocein, MOB like protein phocein, MOB1, mob1 homolog 3, MOB1, Mps One Binder kinase activator like 3, Mob3, MOB4, MOBKL3, MOBL3_HUMAN, mps one binder kinase activator like 3, Mps one binder kinase activator-like 3, Phocein Mob like protein, PHOCN, PREI3, Preimplantation protein 3, RCJMB04_1o21.

Background: Phocein is a 225 amino acid protein encoded by the human gene MOBKL3. Phocein belongs to the MOB1/phocein family and is phosphorylated on serine residues. Phocein is a widely expressed, highly conserved intracellular protein. The sequence of Phocein has limited homology to the sigma subunits from Clathrin adaptor complexes and contains an additional stretch bearing a putative SH3-binding domain. Phocein is usually associated with membranes but can be present in the cytosol, where it behaves as a protein complex. Phocein is the major partner of the striatin family members, which are scaffolding proteins involved in signaling and trafficking. Due to its association with Dynamin via direct interactions with nucleotide diphosphate kinase (NDPK) and Eps15, Phocein has been implicated in vesicular trafficking, acting in particular in the endocytic process.

Gene ID: 25843