C2orf49 antibody (AA 141-232) (HRP)

Catalog No. ABIN1712017

This Rabbit Polyclonal antibody specifically detects C2orf49 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for C2orf49 antibody (AA 141-232) (HRP) (ABIN1712017)

Target: C2orf49 (Chromosome 2 Open Reading Frame 49 (C2orf49))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2orf49 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-C2orf49 Antibody (HRP)

Binding Specificity: AA 141-232

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf49

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C2orf49

Target: C2orf49 (Chromosome 2 Open Reading Frame 49 (C2orf49))

Alternative Name: C2orf49

Background:

Synonyms: Ashwin, asw, Chromosome 2 open reading frame 49, FLJ45759, MGC5509, ASHWN_HUMAN.

Background: C2orf49 (chromosome 2 open reading frame 49), also known as asw, Ashwin, MGC5509 or FLJ45759, is a 232 amino acid member of the ashwin family and is encoded by a gene located on human chromosome 2q12.2. The second largest human chromosome, chromosome 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Gene ID: 79074