DOCK2 antibody (AA 451-550) (HRP)

Catalog No. ABIN1712036

The Rabbit Polyclonal anti-DOCK2 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect DOCK2 in samples from Human.

Quick Overview for DOCK2 antibody (AA 451-550) (HRP) (ABIN1712036)

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DOCK2 Antibody (HRP)

Binding Specificity: AA 451-550

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOCK2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DOCK2

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Alternative Name: DOCK2

Background:

Synonyms: Dedicator of cytokinesis protein 2, DOCK2, KIAA0209

Background: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Gene ID: 1794

UniProt: Q92608