EMSY antibody (AA 721-820) (HRP)

Catalog No. ABIN1712043

The HRP-conjugated Rabbit Polyclonal anti-EMSY antibody (ABIN1712043) specifically detects EMSY in WB, ELISA, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for EMSY antibody (AA 721-820) (HRP) (ABIN1712043)

Target: EMSY (C11orf30) (Chromosome 11 Open Reading Frame 30 (C11orf30))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMSY antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-EMSY Antibody (HRP)

Binding Specificity: AA 721-820

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EMSY

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EMSY

Target: EMSY (C11orf30) (Chromosome 11 Open Reading Frame 30 (C11orf30))

Alternative Name: EMSY

Background:

Synonyms: GL002, C11orf30, BRCA2-interacting transcriptional repressor EMSY, EMSY

Background: Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.

Gene ID: 56946

UniProt: Q7Z589