ZBTB43 antibody (AA 351-450) (HRP)

Catalog No. ABIN1712095

This Rabbit Polyclonal antibody specifically detects ZBTB43 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ZBTB43 antibody (AA 351-450) (HRP) (ABIN1712095)

Target: ZBTB43 (Zinc Finger and BTB Domain Containing 43 (ZBTB43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB43 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ZBTB43 Antibody (HRP)

Binding Specificity: AA 351-450

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB43/ZNF297B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB43

Target: ZBTB43 (Zinc Finger and BTB Domain Containing 43 (ZBTB43))

Alternative Name: ZBTB43/ZNF297B

Background:

Synonyms: RP11489N222, ZBT43_HUMAN, ZBTB22B, ZBTB43, Zinc Finger And BTB Domain Containing 43, Zinc finger and BTB domain-containing protein 22B, Zinc finger and BTB domain-containing protein 43, Zinc Finger Protein 297B, ZnF-x, ZNF297B, ZNFX.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 43 (ZBTB43), also known as ZNF297B or ZBTB22B, is a 467 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB43 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain and the interaction of ZBTB43 with BDP1 suggest that ZBTB43 functions as a transcription regulator.

Gene ID: 23099