GNGT1 antibody (AA 21-70) (HRP)

Catalog No. ABIN1712329

This Rabbit Polyclonal antibody specifically detects GNGT1 in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for GNGT1 antibody (AA 21-70) (HRP) (ABIN1712329)

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNGT1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GNGT1 Antibody (HRP)

Binding Specificity: AA 21-70

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNGT1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GNGT1

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Alternative Name: GNGT1

Background:

Synonyms: G gamma 1, GNG1, GNGT1, Guanine nucleotide binding protein G, Transducin gamma chain, GBG1_HUMAN.

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626], Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

Gene ID: 2792

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction