GNGT1 antibody (AA 21-70)

Catalog No. ABIN1714814

The Rabbit Polyclonal anti-GNGT1 antibody is suitable to detect GNGT1 in samples from Human. It has been validated for ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC.

Quick Overview for GNGT1 antibody (AA 21-70) (ABIN1714814)

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNGT1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-GNGT1 Antibody

Binding Specificity: AA 21-70

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNGT1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GNGT1

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Alternative Name: GNGT1

Background:

Synonyms: G gamma 1, GNG1, GNGT1, Guanine nucleotide binding protein G, Transducin gamma chain, GBG1_HUMAN.

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626], Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

Gene ID: 2792

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction