ADH6 antibody (AA 11-110) (HRP)

Catalog No. ABIN1712480

The Rabbit Polyclonal anti-ADH6 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect ADH6 in samples from Human.

Quick Overview for ADH6 antibody (AA 11-110) (HRP) (ABIN1712480)

Target: ADH6 (Alcohol Dehydrogenase 6 (Class V) (ADH6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADH6 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ADH6 Antibody (HRP)

Binding Specificity: AA 11-110

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADH6

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADH6

Target: ADH6 (Alcohol Dehydrogenase 6 (Class V) (ADH6))

Alternative Name: ADH6

Background:

Synonyms: ADH 5, ADH 6, Adh6, ADH6_HUMAN, Alcohol dehydrogenase 6 class V, Alcohol dehydrogenase 6, Aldehyde reductase, Class V alcohol dehydrogenase 6, UDP GLUCURONOSYLTRANSFERASE 2B10 PRECURSOR, MICROSOMAL.

Background: ADH6 (alcohol dehydrogenase 6), also known as ADH-5, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family. This family of enzymes functions to metabolize a wide variety of substrates such as retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and expressed in the stomach and liver, ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors. ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, suggesting that expression of ADH6 may be under hormonal control. Multiple isoforms of ADH6 exist due to alternative splicing events.

Gene ID: 130