TMEM244 antibody (HRP)

Catalog No. ABIN1712590

Product Details anti-TMEM244 Antibody (HRP)

Target: TMEM244 (Transmembrane Protein 244 (TMEM244))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM244 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf191

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TMEM244

Target: TMEM244 (Transmembrane Protein 244 (TMEM244))

Alternative Name: C6orf191 (TMEM244 Products)

Synonyms: C6orf191 antibody, bA174C7.4 antibody, transmembrane protein 244 antibody, TMEM244 antibody

Background:

Synonyms: bA174C7.4, C6orf191, TM244_HUMAN, Chromosome 6 open reading frame 191, Putative transmembrane protein C6orf191.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf191 gene product has been provisionally designated C6orf191 pending further characterization.

Gene ID: 253582