ERMAP antibody (PE)

Catalog No. ABIN1712690

The Rabbit Polyclonal anti-ERMAP antibody has been validated for FACS. It is suitable to detect ERMAP in samples from Human, Mouse and Rat.

Quick Overview for ERMAP antibody (PE) (ABIN1712690)

Target: ERMAP (erythroblast Membrane-Associated Protein (Scianna Blood Group) (ERMAP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERMAP antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-ERMAP Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ERMAP

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100)

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for ERMAP

Target: ERMAP (erythroblast Membrane-Associated Protein (Scianna Blood Group) (ERMAP))

Alternative Name: Ermap

Background:

ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death.

Subcellular location: Extracellular

Synonyms: ERMAP, ERMAP_HUMAN, Erythroblast membrane associated protein, Erythroid membrane associated protein, Erythroid membrane-associated protein, hERMAP, MGC118810, MGC118811, MGC118812, MGC118813, PRO2801, Radin blood group Rd, Radin blood group antigen, RD, SC, Scianna blood group Sc, Scianna blood group antigen.

Gene ID: 114625