Stabilin 2 (STAB2) antibody (PE)

Catalog No. ABIN1712724

This anti- antibody is a Rabbit Polyclonal antibody detecting in FACS. Suitable for Human, Mouse and Rat.

Quick Overview for Stabilin 2 (STAB2) antibody (PE) (ABIN1712724)

Target: Stabilin 2 (STAB2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: PE

Application: Flow Cytometry (FACS)

Product Details

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Stabilin-2

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100)

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details

Target: Stabilin 2 (STAB2)

Alternative Name: Stabilin 2/STAB 2

Background:

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Subcellular location: Extracellular

Synonyms: FEX2, HARE, FEEL2, FELL2, FELE-2, Stabilin-2, FAS1 EGF-like and X-link domain-containing adhesion molecule 2, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2, FEEL-2, Hyaluronan receptor for endocytosis, STAB2, FELL

Gene ID: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process