GPR124 antibody (PE)

Catalog No. ABIN1712768

The Rabbit Polyclonal anti-GPR124 antibody has been validated for . It is suitable to detect GPR124 in samples from Human, Mouse and Rat.

Quick Overview for GPR124 antibody (PE) (ABIN1712768)

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR124 antibody is conjugated to PE

Application: Please inquire

Product Details anti-GPR124 Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 124

Isotype: IgG

Application Details

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Alternative Name: Gpr124/Tem5

Background:

Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Subcellular location: Extracellular

Synonyms: DKFZp434C211, DKFZp434J0911, FLJ14390, G protein coupled receptor 124, G-protein coupled receptor 124, GP124_HUMAN, GPR 124, GPR124, KIAA1531, TEM 5, TEM5, Tumor endothelial marker 5, Tumor endothelial marker 5 precursor, GPCR GPR124.

Gene ID: 25960