CTLA4 antibody (C-Term) (PE-Cy5)

Catalog No. ABIN1713013

This Rabbit Polyclonal antibody specifically detects CTLA4 in FACS and WB. It exhibits reactivity toward Human, Mouse, Rat, Cow and Dog.

Quick Overview for CTLA4 antibody (C-Term) (PE-Cy5) (ABIN1713013)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTLA4 antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS), Western Blotting (WB)

Product Details anti-CTLA4 Antibody (PE-Cy5)

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTLA-4/CD152

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name: CTLA4

Background:

Synonyms: CD, GSE, GRD4, CD152, CTLA-4, IDDM12, CELIAC3, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA4

Background: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

Gene ID: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints