GPR124 antibody (PE-Cy7)

Catalog No. ABIN1713304

This Rabbit Polyclonal antibody specifically detects GPR124 in FACS. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig and Cow.

Quick Overview for GPR124 antibody (PE-Cy7) (ABIN1713304)

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR124 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Product Details anti-GPR124 Antibody (PE-Cy7)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)

Purification: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 124

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Comment:

Excitation / Emission wavelength: 496,565nm / 774nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Sodium azide.

Storage: 4 °C

Storage Comment: Store at 4 °C for 12 months

Expiry Date: 12 months

Target Details for GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Alternative Name: GPR124

Background: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Gene ID: 25960