Complement C3c Alpha' Chain Fragment 1 (AA 749-850) antibody

Catalog No. ABIN1713467

The Rabbit Polyclonal anti-Complement C3c Alpha' Chain Fragment 1 antibody is suitable to detect Complement C3c Alpha' Chain Fragment 1 in samples from Human. It has been validated for IF (cc), IF (p), ELISA, IHC (fro) and ICC.

Quick Overview for Complement C3c Alpha' Chain Fragment 1 (AA 749-850) antibody (ABIN1713467)

Target: Complement C3c Alpha' Chain Fragment 1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details

Binding Specificity: AA 749-850

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details

Target: Complement C3c Alpha' Chain Fragment 1

Background:

Synonyms: Acylation stimulating protein, ASP, C3, C3a anaphylatoxin, Complement C3 alpha chain, Complement C3, Complement C3 precursor, Complement component 3, Complement component C3, Complement factor 3, Plp, Complement C3c alpha' chain fragment 1, CO3_HUMAN.

Background: The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

Gene ID: 718