Orexin A antibody

Catalog No. ABIN1713564

This anti-Orexin A antibody is a Rabbit Polyclonal antibody detecting Orexin A in WB, IF (p) and IHC (p). Suitable for Human.

Quick Overview for Orexin A antibody (ABIN1713564)

Target: Orexin A (OXA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Orexin A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Orexin A Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Orexin A

Isotype: IgG

Application Details

Application Notes: WB (1:100-500),IHC-P (1:100-500),IF (p) (1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Orexin A

Target: Orexin A (OXA)

Alternative Name: Orexin A

Background:

Synonyms: HCRT 1, HCRT, HCRT1, HCRT2, Hypocretin orexin neuropeptide precursor, Hypocretin 1, Hypocretin 2, Hypocretin A, Hypocretin, Hypocretin neuropeptide precursor, Hypocretin1, NRCLP1, Orexin A, Orexin, Orexin B, Orexin precursor, OrexinA, OX, PPORX, PPOX, PREPROOREXIN, OREX_HUMAN.

Background: Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.

Gene ID: 3060

Pathways: Synaptic Membrane, Feeding Behaviour