GPR45 antibody (AA 251-350)

Catalog No. ABIN1713827

The Rabbit Polyclonal anti-GPR45 antibody has been validated for WB, IHC (p), ELISA, ICC, IF (cc), IF (p) and IHC (fro). It is suitable to detect GPR45 in samples from Mouse.

Quick Overview for GPR45 antibody (AA 251-350) (ABIN1713827)

Target: GPR45 (G Protein-Coupled Receptor 45 (GPR45))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR45 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPR45 Antibody

Binding Specificity: AA 251-350

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR45

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GPR45

Target: GPR45 (G Protein-Coupled Receptor 45 (GPR45))

Alternative Name: GPR45

Background:

Synonyms: G protein coupled receptor 45, High affinity lysophosphatidic acid receptor, Probable G protein coupled receptor 45, GPCR 45, PSP24 1, PSP24 alpha, PSP24, PSP24ALPHA, PSP241, PSP24A.

Background: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 54 (GPR54), a member of the rhodopsin family of GCPRs, is the receptor for the Kiss1 gene product, metastin. Mutations in GPCR54 are associated with a lack of puberty onset and autosomal recessive idiopathic hypogonadotropic hypogonadism, a deficient or decreased function of the gonads. Proper function of GRP54 is essential for puberty. In the rat, GRP54 is expressed in the liver, intestine and most areas of the brain, while in the human it is expressed in the placenta, pituitary, pancreas and spinal cord.

Gene ID: 11250