Sorting Nexin 4 antibody (AA 351-450)

Catalog No. ABIN1713903

This anti-Sorting Nexin 4 antibody is a Rabbit Polyclonal antibody detecting Sorting Nexin 4 in WB, ELISA, IF (cc), IF (p), IHC (p), ICC and IHC (fro). Suitable for Human.

Quick Overview for Sorting Nexin 4 antibody (AA 351-450) (ABIN1713903)

Target: Sorting Nexin 4 (SNX4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorting Nexin 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Sorting Nexin 4 Antibody

Binding Specificity: AA 351-450

Predicted Reactivity: Human,Mouse,Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNX4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Sorting Nexin 4

Target: Sorting Nexin 4 (SNX4)

Alternative Name: SNX4

Background:

Synonyms: ATG24B, SNX 4, snx4, SNX4_HUMAN, Sorting nexin 4, Sorting nexin-4.

Background: SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

Gene ID: 8723