GBAS antibody (AA 21-120)

Catalog No. ABIN1714000

This Rabbit Polyclonal antibody specifically detects GBAS in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It exhibits reactivity toward Human.

Quick Overview for GBAS antibody (AA 21-120) (ABIN1714000)

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-GBAS Antibody

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBAS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GBAS

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Alternative Name: GBAS

Background:

Synonyms: 4 nitrophenylphosphatase domain and non neuronal SNAP25 like 2, gbas, Glioblastoma amplied sequence, Glioblastoma-amplied sequence, NIPS2_HUMAN, Nipsnap homolog 2, NipSnap2, Protein NipSnap homolog 2.

Background: NIPSNAP2 is a 286 amino acid protein that is abundantly expressed in heart and skeletal muscle. Belonging to the NIPSNAP family, NIPSNAP2 may be involved in vesicular transport. NIPSNAP2 contains a signal peptide, a transmembrane domain and two tyrosine phosphorylation sites. NIPSNAP2 is encoded by a gene mapping to human chromosome 7p11.2. Chromosomal region 7p12 is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor. Human chromosome 7 houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Gene ID: 2631

Pathways: Ribonucleoside Biosynthetic Process