IFT122 antibody (AA 1-100)

Catalog No. ABIN1714062

This anti-IFT122 antibody is a Rabbit Polyclonal antibody detecting IFT122 in WB, IF (cc), IF (p), ELISA, IHC (p), ICC and IHC (fro). Suitable for Human.

Quick Overview for IFT122 antibody (AA 1-100) (ABIN1714062)

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT122 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IFT122 Antibody

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFT122

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IFT122

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Alternative Name: T122

Background:

Synonyms: CED, 122_HUMAN, T122, Intraflagellar transport 122 homolog Chlamydomonas, Intraflagellar transport protein 122 homolog, SPG, WD repeat domain 10, WD repeat-containing protein 10, WD repeat-containing protein 140, WDR10, WDR10p, WDR140.

Background: IFT122 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Pathways: Tube Formation, Embryonic Body Morphogenesis