C1orf55 antibody (AA 51-150)

Catalog No. ABIN1714123

This Rabbit Polyclonal antibody specifically detects C1orf55 in WB, IF (cc), IF (p), IHC (p), ELISA, IHC (fro) and ICC. It exhibits reactivity toward Human.

Quick Overview for C1orf55 antibody (AA 51-150) (ABIN1714123)

Target: C1orf55 (Chromosome 1 Open Reading Frame 55 (C1orf55))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf55 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-C1orf55 Antibody

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf55

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C1orf55

Target: C1orf55 (Chromosome 1 Open Reading Frame 55 (C1orf55))

Alternative Name: C1orf55

Background:

Synonyms: C1orf55, CA055_HUMAN, Chromosome 1 open reading frame 55, dJ671D7.1, FLJ35382, Hypothetical protein LOC163859, RP4 671D7.1, UPF0667 protein C1orf55.

Background: Belonging to the UPF0667 family, C1orf55 is a 451 amino acid protein that is phosphorylated upon DNA damage, likely by Atm or ATR. There are three different isoforms of C1orf55 that are produced as a result of alternative splicing events. The gene encoding C1orf55 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Gene ID: 163859