IL-19 antibody (AA 81-177)

Catalog No. ABIN1714204

This Rabbit Polyclonal antibody specifically detects IL-19 in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for IL-19 antibody (AA 81-177) (ABIN1714204)

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-19 Antibody

Binding Specificity: AA 81-177

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-19/NG.1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IL-19 antibody (ABIN1714204)

Cooley, Chauhan, Donneyz, Marriott: "Astrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member." in: Glia, Vol. 62, Issue 5, pp. 818-28, (2014) (PubMed).

Target Details for IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Alternative Name: IL-19

Background:

Synonyms: Interleukin-19, IL 10C, IL 19, Interleukin 19, MDA1,ZMDA1, IL-19, Melanoma dferentiation-associated protein-like protein, NG.1, IL19_HUMAN.

Background: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq].

Gene ID: 29949