BAF53A antibody (AA 101-200)

Catalog No. ABIN1714278

This anti-BAF53A antibody is a Rabbit Polyclonal antibody detecting BAF53A in ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). Suitable for Mouse and Rat.

Quick Overview for BAF53A antibody (AA 101-200) (ABIN1714278)

Target: BAF53A (Actin-Like 6A (BAF53A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAF53A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BAF53A Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BAF53A

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BAF53A

Target: BAF53A (Actin-Like 6A (BAF53A))

Alternative Name: BAF53A

Background:

Synonyms: 53 kDa BRG1 associated factor A, Actin like 6A, Actin like protein 6A, Actin related protein, Actin related protein Baf53a, ACTL 6, ACTL 6A, ACTL6, ACTL6A, ARPN BETA, ArpNbeta, BAF 53, BAF 53A, BAF complex 53 kDa subunit, BAF53, BRG1 associated factor 53A, BRG1 associated factor, BRG1/brm associated factor 53A, hArpN beta, INO80K, MGC5382.

Background: The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPn beta), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.

Gene ID: 86

Pathways: Chromatin Binding, Photoperiodism