SNX6 antibody (AA 211-310)

Catalog No. ABIN1714321

This Rabbit Polyclonal antibody specifically detects SNX6 in ELISA, WB, ICC, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for SNX6 antibody (AA 211-310) (ABIN1714321)

Target: SNX6 (Sorting Nexin 6 (SNX6))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SNX6 Antibody

Binding Specificity: AA 211-310

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNX6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SNX6

Target: SNX6 (Sorting Nexin 6 (SNX6))

Alternative Name: SNX6

Background:

Synonyms: Sorting Nexin 6, TFAF2, TRAF4 Associated Factor 2, SNX6_HUMAN.

Background: Two related proteins, TRAF1 and TRAF2 (TNF receptor-associated factors 1 and 2, respectively), form a heterodimeric complex that associates with the cytoplasmic domain of the tumor necrosis factor (TNF) receptor type 2 (1). A third member of this family, TRAF3 (also designated CD40bp or CRAF1) associates with the cytoplasmic domain of CD40 (2). Additional membersof the TRAF/CRAF family of signaling intermediates include TRAF4 (also designated CART1), TRAF5 and TRAF6 (3-5). TRAF4 associated factor 2 (TRAF4-AF2), also designated sorting nexin 6 (SNX6), is a member of the sorting nexin family of molecules, which are widely expressed and associate with various receptor (6).

Gene ID: 58533

Pathways: EGFR Signaling Pathway