GCN1L1 antibody (AA 751-850)

Catalog No. ABIN1714545

The Rabbit Polyclonal anti-GCN1L1 antibody (ABIN1714545) specifically detects GCN1L1 in WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. The antibody is reactive with Human samples.

Quick Overview for GCN1L1 antibody (AA 751-850) (ABIN1714545)

Target: GCN1L1 (GCN1 General Control of Amino-Acid Synthesis 1-Like 1 (Yeast) (GCN1L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCN1L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-GCN1L1 Antibody

Binding Specificity: AA 751-850

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Gcn1l1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GCN1L1

Target: GCN1L1 (GCN1 General Control of Amino-Acid Synthesis 1-Like 1 (Yeast) (GCN1L1))

Alternative Name: Gcn1l1

Background:

Synonyms: GCN1, GCN1 general control of amino acid synthesis yeast homolog like, GCN1 general control of amino acid synthesis 1 yeast like 1, GCN1 general control of amino acid synthesis 1 like 1, GCN1 general control of amino acid synthesis 1 like 1 yeast, GCN1 like protein 1, GCN1L, HsGCN1, GCN1L_HUMAN.

Background: GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 10985