ZBTB43 antibody (AA 351-450)

Catalog No. ABIN1714580

The Rabbit Polyclonal anti-ZBTB43 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It is suitable to detect ZBTB43 in samples from Human.

Quick Overview for ZBTB43 antibody (AA 351-450) (ABIN1714580)

Target: ZBTB43 (Zinc Finger and BTB Domain Containing 43 (ZBTB43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB43 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-ZBTB43 Antibody

Binding Specificity: AA 351-450

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB43/ZNF297B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB43

Target: ZBTB43 (Zinc Finger and BTB Domain Containing 43 (ZBTB43))

Alternative Name: ZBTB43/ZNF297B

Background:

Synonyms: RP11489N222, ZBT43_HUMAN, ZBTB22B, ZBTB43, Zinc Finger And BTB Domain Containing 43, Zinc finger and BTB domain-containing protein 22B, Zinc finger and BTB domain-containing protein 43, Zinc Finger Protein 297B, ZnF-x, ZNF297B, ZNFX.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 43 (ZBTB43), also known as ZNF297B or ZBTB22B, is a 467 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB43 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain and the interaction of ZBTB43 with BDP1 suggest that ZBTB43 functions as a transcription regulator.

Gene ID: 23099