RPP25L antibody (AA 1-100)

Catalog No. ABIN1714606

This Rabbit Polyclonal antibody specifically detects RPP25L in WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for RPP25L antibody (AA 1-100) (ABIN1714606)

Target: RPP25L (Ribonuclease P/MRP 25 Subunit-Like (RPP25L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPP25L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-RPP25L Antibody

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf23

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RPP25L

Target: RPP25L (Ribonuclease P/MRP 25 Subunit-Like (RPP25L))

Alternative Name: C9orf23

Background:

Synonyms: Alba like protein C9orf23, bA296L22.5, C9orf23, MGC29635, Ribonuclease P protein subunit p25 like protein, Ribonuclease P/MRP 25 kDa subunit like, RNase P protein subunit like p25, Rpp25 like protein, RPP25L, RP25L_HUMAN.

Background: C9orf23 (chromosome 9 open reading frame 23) is a 163 amino acid protein that belongs to the histone-like Alba family and is encoded by a gene that maps to human chromosome 9p13.3. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 138716