TMEM252 antibody (AA 31-130)

Catalog No. ABIN1714609

This Rabbit Polyclonal antibody specifically detects TMEM252 in IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for TMEM252 antibody (AA 31-130) (ABIN1714609)

Target: TMEM252 (Transmembrane Protein 252 (TMEM252))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM252 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-TMEM252 Antibody

Binding Specificity: AA 31-130

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf71

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TMEM252

Target: TMEM252 (Transmembrane Protein 252 (TMEM252))

Alternative Name: C9orf71

Background:

Synonyms: C9orf71, Chromosome 9 open reading frame 71, TM252_HUMAN, MGC34760, RP11-274B18.1, TMEM252, Transmembrane protein 252, Transmembrane protein C9orf71.

Background: Chromosome 9 consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf71 gene product has been provisionally designated C9orf71 pending further characterization.

Gene ID: 169693