DAAM2 antibody (AA 161-260)

Catalog No. ABIN1714722

The Rabbit Polyclonal anti-DAAM2 antibody (ABIN1714722) specifically detects DAAM2 in ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. The antibody is reactive with Human samples.

Quick Overview for DAAM2 antibody (AA 161-260) (ABIN1714722)

Target: DAAM2 (Dishevelled Associated Activator of Morphogenesis 2 (DAAM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAAM2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-DAAM2 Antibody

Binding Specificity: AA 161-260

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAAM2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DAAM2

Target: DAAM2 (Dishevelled Associated Activator of Morphogenesis 2 (DAAM2))

Alternative Name: DAAM2

Background:

Synonyms: DAAM2, DAAM2_HUMAN, Disheveled-associated activator of morphogenesis 2, dishevelled associated activator of morphogenesis 2, dJ90A20A.1, KIAA0381, MGC90515, RP1 278E11.1.

Background: DAAM2 is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Gene ID: 23500