ZFP36L1 antibody (AA 101-200)

Catalog No. ABIN1714898

The Rabbit Polyclonal anti-ZFP36L1 antibody has been validated for ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It is suitable to detect ZFP36L1 in samples from Rat.

Quick Overview for ZFP36L1 antibody (AA 101-200) (ABIN1714898)

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP36L1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-ZFP36L1 Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZFP36L1/ERF1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZFP36L1

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Alternative Name: ZFP36L1/ERF1

Background:

Synonyms: Berg36, BRF1, Butyrate response factor 1, C3H1 type-like 1, cMG1, Early response factor Berg36, EGF response factor 1, EGF-response factor 1, ERF 1, ERF-1, ERF1, Protein TIS11B, RNF162B, TIS11B, TISB_HUMAN, ZFP36L1, Zinc finger protein 36, Zinc finger protein 36 C3H type like 1, zinc finger protein C3H type 36 like 1.

Background: TIS11B is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3?-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.

Gene ID: 677