C1orf114 antibody (AA 101-200)

Catalog No. ABIN1714971

This anti-C1orf114 antibody is a Rabbit Polyclonal antibody detecting C1orf114 in ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. Suitable for Human and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for C1orf114 antibody (AA 101-200) (ABIN1714971)

Target: C1orf114 (CCDC181) (Coiled-Coil Domain Containing 181 (CCDC181))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf114 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-C1orf114 Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf114

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-C1orf114 antibody (ABIN1714971)

Schwarz, Prieler, Schmid, Grzmil, Neesen: "Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia." in: European journal of cell biology, Vol. 96, Issue 3, pp. 276-288, (2018) (PubMed).

Target Details for C1orf114

Target: C1orf114 (CCDC181) (Coiled-Coil Domain Containing 181 (CCDC181))

Alternative Name: C1orf114

Background:

Synonyms: C1orf114, CA114_HUMAN, chromosome 1 open reading frame 114, RP1-206D15.2, Uncharacterized protein C1orf114.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf114 gene product has been provisionally designated C1orf114 pending further characterization.

Gene ID: 57821