GLRX5 antibody (AA 51-157)

Catalog No. ABIN1715024

The Rabbit Polyclonal anti-GLRX5 antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It is suitable to detect GLRX5 in samples from Human. There is 1 publication available.

Quick Overview for GLRX5 antibody (AA 51-157) (ABIN1715024)

Target: GLRX5 (Glutaredoxin 5 (GLRX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-GLRX5 Antibody

Binding Specificity: AA 51-157

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glutaredoxin 5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GLRX5 antibody (ABIN1715024)

Rychtarcikova, Lettlova, Tomkova, Korenkova, Langerova, Simonova, Zjablovskaja, Alberich-Jorda, Neuzil, Truksa: "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." in: Oncotarget, Vol. 8, Issue 4, pp. 6376-6398, (2016) (PubMed).

Target Details for GLRX5

Target: GLRX5 (Glutaredoxin 5 (GLRX5))

Alternative Name: Glutaredoxin 5

Background:

Synonyms: C14orf87, Chromosome 14 open reading frame 87, FLB4739, GLRX 5, Glrx5, GLRX5_HUMAN, Glutaredoxin 5 homolog, Glutaredoxin related protein 5, Glutaredoxin-related protein 5, Glutaredoxin5, GRX5, MGC14129, mitochondrial, Monothiol glutaredoxin-5, PRO1238.

Background: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.

Gene ID: 51218

Pathways: Cell RedoxHomeostasis