GLRX5 antibody (AA 51-157)

Catalog No. ABIN1715024

There is 1 publication for this product available. The Rabbit Polyclonal anti-GLRX5 antibody is suitable to detect GLRX5 in samples from Human. It has been validated for WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC.

Quick Overview for GLRX5 antibody (AA 51-157) (ABIN1715024)

Target: GLRX5 (Glutaredoxin 5 (GLRX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-GLRX5 Antibody

Binding Specificity: AA 51-157

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glutaredoxin 5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GLRX5 antibody (ABIN1715024)

Rychtarcikova, Lettlova, Tomkova, Korenkova, Langerova, Simonova, Zjablovskaja, Alberich-Jorda, Neuzil, Truksa: "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." in: Oncotarget, Vol. 8, Issue 4, pp. 6376-6398, (2016) (PubMed).

Target Details for GLRX5

Target: GLRX5 (Glutaredoxin 5 (GLRX5))

Alternative Name: Glutaredoxin 5

Background:

Synonyms: C14orf87, Chromosome 14 open reading frame 87, FLB4739, GLRX 5, Glrx5, GLRX5_HUMAN, Glutaredoxin 5 homolog, Glutaredoxin related protein 5, Glutaredoxin-related protein 5, Glutaredoxin5, GRX5, MGC14129, mitochondrial, Monothiol glutaredoxin-5, PRO1238.

Background: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.

Gene ID: 51218

Pathways: Cell RedoxHomeostasis