MAML3 antibody (AA 931-1030)

Catalog No. ABIN1715044

This Rabbit Polyclonal antibody specifically detects MAML3 in IHC (p), IF (cc), IF (p), ELISA, IHC (fro) and ICC. It exhibits reactivity toward Human.

Quick Overview for MAML3 antibody (AA 931-1030) (ABIN1715044)

Target: MAML3 (Mastermind-Like 3 (MAML3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAML3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-MAML3 Antibody

Binding Specificity: AA 931-1030

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAML3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MAML3

Target: MAML3 (Mastermind-Like 3 (MAML3))

Alternative Name: MAML3

Background:

Synonyms: AV234550, BC049812, CAGH3, ERDA3, GDN, KIAA1816, MAM 2, MAM2, mastermind like 3 Drosophila, MGC59565, mKIAA1816, TNRC3, MAML3_HUMAN.

Background: The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1.