ANK3
Reactivity: Human
WB, ICC, IF
Host: Mouse
Monoclonal
S106-20
Atto 594
Application Notes
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: IHC20 μg/mL WB1 - 2 μg/mL
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS pH 7.4, 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Dilute in PBS or medium that is identical to that used in the assay system.
Storage
-20 °C
Storage Comment
Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Expiry Date
12 months
Target
Ankyrin G (ANK3)
(Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
Alternative Name
Ankyrin-G
Background
Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton. Ankyrins have binding sites for the beta subunit of spectrin and for at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers, and ion transporters in the plasma membrane.