Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) antibody

Catalog No. ABIN1721485

This Mouse Monoclonal antibody specifically detects in IHC and WB. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) antibody (ABIN1721485)

Target: Cav3.1 Ca2+ Channel

Reactivity: Mouse, Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: S178A-9

Product Details

Binding Specificity: AA 2052-2172, C-Term

Specificity: Reacts withhuman, mouse, and rat Cav3.1. Does not cross-react with Cav3.2.

Purification: Purified

Immunogen: Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).

Isotype: IgG1

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1 - 2 μg/mL) IHC(1 - 10 μg/mL)

Positive control: Rat brain membranes

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Cav3.1 Ca2+ Channel

Background: Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and anti-epileptics and possibly in some anesthetics and antipsychotics.

Voltage-dependent T-type calcium channel subunit alpha-1G Cav3.1c NBR13 Voltage-gated calcium channel subunit alpha Cav3.1 Gene name: CACNA1G, KIAA1123 Ca(V)T.1, Cav3.1, NBR13

Gene ID: 8913

UniProt: O43497