IL-6 Receptor antibody

Catalog No. ABIN1722535

This Mouse Monoclonal antibody specifically detects IL-6 Receptor in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for IL-6 Receptor antibody (ABIN1722535)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: B-N12

Product Details anti-IL-6 Receptor Antibody

Specificity: Reacts with both soluble and membrane bound human Interleukin 6 Receptor alpha subunit (IL-6 Ra)

Cross-Reactivity (Details): No effect on IL-6 induced proliferation of XG-1 cell line

Purification: Purified (liquid chromatography)

Sterility: Sterile filtered

Immunogen: gp80 transfected CHO cell line

Isotype: IgG1

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.

IP, WB and IHC: not tested Suitable for flow cytometry

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, sterile-filtered (0.22 μm), Azide free

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at +2-8°C for 12 months. For longer storage, freeze aliquots

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: CD126 / IL-6R

Gene ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints