ASPSCR1 antibody

Catalog No. ABIN1724649

Cited in 1 publication. The Mouse Monoclonal anti-ASPSCR1 antibody (Clone 4A11A6G11) (ABIN1724649) specifically detects ASPSCR1 in WB and ELISA. The antibody is reactive with Mouse samples.

Quick Overview for ASPSCR1 antibody (ABIN1724649)

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ASPSCR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 4A11A6G11

Product Details anti-ASPSCR1 Antibody

Purpose: Mouse TUG Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of TUG expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ASPSCR1 antibody (ABIN1724649)

Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

Target Details for ASPSCR1

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Alternative Name: TUG

Background: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

UniProt: Q9BZE9