Apolipoprotein M antibody

Catalog No. ABIN1724662

This Mouse Monoclonal antibody specifically detects Apolipoprotein M in ELISA and ICC. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for Apolipoprotein M antibody (ABIN1724662)

Target: Apolipoprotein M (APOM)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Apolipoprotein M antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Clone: 10C3G5

Product Details anti-Apolipoprotein M Antibody

Purpose: ApoM Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of ApoM expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Apolipoprotein M antibody (ABIN1724662)

Wolfrum, Poy, Stoffel: "Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis." in: Nature medicine, Vol. 11, Issue 4, pp. 418-22, (2005) (PubMed).

Xu, Nilsson-Ehle, Ahrén: "Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects." in: The Journal of nutritional biochemistry, Vol. 15, Issue 10, pp. 579-82, (2004) (PubMed).

Zhang, Jiao, Hurtig, Dong, Zheng, Luo, Nilsson-Ehle, Ye, Xu: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, (2004) (PubMed).

Target Details for Apolipoprotein M

Target: Apolipoprotein M (APOM)

Alternative Name: ApoM

Background: ApoM (apolipoprotein M, also designated G3a or NG20), with 188-amino acid protein(about 21 kDa), is an apolipoprotein and member of the lipocalin protein family. The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro, Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment. Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs, and also found in triglyceride-rich lipoproteins and LDLs.

Molecular Weight: 21 kDa

Gene ID: 55937

UniProt: O95445