CBX8 antibody (AA 17-222)

Catalog No. ABIN1724765

The Mouse Monoclonal anti-CBX8 antibody has been validated for ELISA and FACS. It is suitable to detect CBX8 in samples from Human. There is 1 publication available.

Quick Overview for CBX8 antibody (AA 17-222) (ABIN1724765)

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 9C3D4

Product Details anti-CBX8 Antibody

Binding Specificity: AA 17-222

Purpose: CBX8 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CBX8 (AA: 17-222 ) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CBX8 antibody (ABIN1724765)

Dietrich, Bracken, Trinh, Schjerling, Koseki, Rappsilber, Helin, Hansen: "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8

Background: Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.

Molecular Weight: 43.4 kDa

Gene ID: 57332

UniProt: Q9HC52