KLF1 antibody (AA 208-362)

Catalog No. ABIN1724828

The Mouse Monoclonal anti-KLF1 antibody has been validated for ELISA, IHC and FACS. It is suitable to detect KLF1 in samples from Human. There are 2+ publications available.

Quick Overview for KLF1 antibody (AA 208-362) (ABIN1724828)

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 1B6A3

Product Details anti-KLF1 Antibody

Binding Specificity: AA 208-362

Purpose: KLF1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human KLF1 (AA: 208-362) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-KLF1 antibody (ABIN1724828)

Alhashem, Vinjamur, Basu, Klingmüller, Gaensler, Lloyd: "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).

Zhou, Liu, Sun, Pawlik, Townes: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).

Target Details for KLF1

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Alternative Name: KLF1

Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.

Molecular Weight: 38.2 kDa

UniProt: Q13351