This Mouse Monoclonal antibody specifically detects NAPSA in WB, IHC and ELISA. It exhibits reactivity toward Human and Ratand has been mentioned in 1 publication.
Purified antibody in PBS with 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Aikawa, Kawahara, Hattori, Yamaguchi, Abe, Taira, Azuma, Kage: "Comparison of the expression levels of napsin A, thyroid transcription factor-1, and p63 in nonsmall cell lung cancer using cytocentrifuged bronchial brushings." in: Cancer cytopathology, Vol. 119, Issue 5, pp. 335-45, (2011) (PubMed).
Target
NAPSA
(Napsin A Aspartic Peptidase (NAPSA))
Alternative Name
NAPSA
Background
The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.